Announcement
Thank you for attending THSNA 2026. The virtual meeting is now closed.
Thank you for attending THSNA 2026. The virtual meeting is now closed.
Presentation Details
| Platelet function evaluation using microfluidics Nathan Sniadecki. |
Abstract
Platelets generate cytoskeletal forces to adhere to the extracellular matrix at the wall of an injury blood vessel. They also generate these forces when they aggregate together to form a nascent thrombus structure. These forces are driven by the sliding interaction between myosin and actin filaments and are nanoscale in magnitude. I will discuss the engineering approaches my lab has developed to measure the contractile forces produced by platelets during hemostasis and thrombosis as it pertains to antiplatelet medications, trauma-induced coagulopathy, storage conditions for platelet transfusions, and mechanobiology.
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